Some common drug which are approved from FDA which are used in covid-19 such as remdesivir
What are drug used in Covid-19 ?
COVID-19 is a highly infectious disease that can cause life threatening symptoms. There is currently no cure, but some treatments are available to help manage it.
In this article, we discuss the treatment drugs which are available for COVID-19 in the hospital.
There are many drugs which is used for covid-19 some of them
are as
follows -:
Dexamethasone
It is a corticosteroid that can help reduce the length of time
on a ventilator and save lives of patients with severe and critical illness. It
also work as anti-inflammatory effect. But it cannot be in used just because it
increased the risk of viral infections.
Hydroxychloroquine
Hydroxychloroquine or Chloroquine,
a common treatment for malaria and certain autoimmune diseases, has been studied as a
preventative treatment for COVID-19. Evidence from these studies shows that Hydroxychloroquine has little
to no impact on illness, hospitalization, or death
What are the drugs which FDA-approved for covid-19 ?
FDA stands for Food &
Drug Administration and has approved the two drug (Ivermectin) and (remdesivir)
for adults and certain pediatric patients with COVID-19 who are sick enough to
need hospitalization. Remdesivir should only be administered in a hospital or
in a health care setting capable of providing acute care comparable to
inpatient hospital care.
There are currently many clinical trials in process to
study other potential therapies, such as monoclonal antibodies, for
COVID-19.
Ivermectin
Ivermectin, an FDA-approved
anti-parasitic agent, was found to be an inhibitor of SARS-CoV-2 replication in
the laboratory.
Ivermectin may be effective
for the treatment of early-onset mild COVID-19 in adult patients
Early viral clearance of
SARS-CoV-2 was observed in ivermectin treated patients
Larger trials will be needed
to confirm these preliminary findings
Remdesivir
Originally, it was created as a
possible treatment for hepatitis. In 2014, it was studied as a possible
treatment for the Ebola virus. Since then, its effectiveness against other
coronaviruses was studied as viruses emerged. Researchers found remdesivir to
be effective against severe acute respiratory syndrome (SARS) and Middle East
respiratory syndrome (MERS) although research was only conducted in test tubes
and on animals, not in human
What is Remdesivir and how it is useful in covid-19 ?
As we see earlier that remdesivir is made for hepatitis and in 2014 it is studied for ebola virus. it is a antiviral drug so it is studied for covid.
Lets see how remdesivir is useful in covid-19
The drug prevents the virus from
producing a particular enzyme that is necessary for the virus to replicate
itself. Once this happens, the virus is no longer able to spread within the
body.
Research shows that when
patients with moderate COVID-19 receive remdesivir, their symptoms improve more
quickly. The drug has also been shown to shorten the duration of patient
hospital stays. Among severely ill COVID-19 patients, remdesivir has been
associated with fewer deaths
What is the actual dose of remdesivir ?
The dosage of
the drug is through daily infusion for about ten days. At present, the drug has
not been approved by health officials across the globe. Further, the drug was
initially being used for Ebola, making the supply low. Many countries attempt
to get access to the drug in the hopes of treating their COVID-19 patients
Investigators
randomly assigned 397 coronavirus patients with an oxygen saturation of 94% or
less and radiologic evidence of pneumonia to receive intravenous remdesivir,
with a 200-milligram (mg) loading dose followed by 100 mg daily, for the next 4
or 9 days.
No significant difference in outcomes
At
baseline, the 197 patients in the 10-day group had significantly more severe
illness than the 200 patients in the 5-day group
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