Common drugs for covid-19

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Apr 11 '21 | By (Swapnil) Amrita Health Staff | Views: 460 | Comments: 4
Common drugs for covid-19

Some common drug which are approved from FDA which are used in covid-19 such as remdesivir



What are drug used in Covid-19 ?



COVID-19 is a highly infectious disease that can cause life threatening symptoms. There is currently no cure, but some treatments are available to help manage it.

In this article, we discuss the treatment drugs which are available for COVID-19  in the hospital.


There are many drugs which is used for covid-19 some of them are  as  follows  -:


Dexamethasone


It is a corticosteroid that can help reduce the length of time on a ventilator and save lives of patients with severe and critical illness. It also work as anti-inflammatory effect. But it cannot be in used just because it increased the risk of viral infections.  


  

Hydroxychloroquine


Hydroxychloroquine or Chloroquine, a common treatment for malaria and certain autoimmune diseases, has been studied as a preventative treatment for COVID-19. Evidence from these studies shows that Hydroxychloroquine has little to no impact on illness, hospitalization, or death




What are the drugs which FDA-approved  for covid-19 ?

 

FDA stands for Food & Drug Administration and has approved the two drug (Ivermectin) and  (remdesivir) for adults and certain pediatric patients with COVID-19 who are sick enough to need hospitalization. Remdesivir should only be administered in a hospital or in a health care setting capable of providing acute care comparable to inpatient hospital care.

There are currently many clinical trials in process to study other potential therapies, such as monoclonal antibodies, for COVID-19.


Ivermectin



Ivermectin, an FDA-approved anti-parasitic agent, was found to be an inhibitor of SARS-CoV-2 replication in the laboratory.

Ivermectin may be effective for the treatment of early-onset mild COVID-19 in adult patients

Early viral clearance of SARS-CoV-2 was observed in ivermectin treated patients

Larger trials will be needed to confirm these preliminary findings


Remdesivir




Originally, it was created as a possible treatment for hepatitis. In 2014, it was studied as a possible treatment for the Ebola virus. Since then, its effectiveness against other coronaviruses was studied as viruses emerged. Researchers found remdesivir to be effective against severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) although research was only conducted in test tubes and on animals, not in human



What is Remdesivir and how it is useful in covid-19 ?


As we see earlier that remdesivir is made for hepatitis and in 2014 it is studied for ebola virus. it is a antiviral drug so it is studied for covid.


Lets see how remdesivir is useful in covid-19

 

The drug prevents the virus from producing a particular enzyme that is necessary for the virus to replicate itself. Once this happens, the virus is no longer able to spread within the body.


Research shows that when patients with moderate COVID-19 receive remdesivir, their symptoms improve more quickly. The drug has also been shown to shorten the duration of patient hospital stays. Among severely ill COVID-19 patients, remdesivir has been associated with fewer deaths 



What is the actual dose of remdesivir ?



 

The dosage of the drug is through daily infusion for about ten days. At present, the drug has not been approved by health officials across the globe. Further, the drug was initially being used for Ebola, making the supply low. Many countries attempt to get access to the drug in the hopes of treating their COVID-19 patients


 Investigators randomly assigned 397 coronavirus patients with an oxygen saturation of 94% or less and radiologic evidence of pneumonia to receive intravenous remdesivir, with a 200-milligram (mg) loading dose followed by 100 mg daily, for the next 4 or 9 days.


No significant difference in outcomes

At baseline, the 197 patients in the 10-day group had significantly more severe illness than the 200 patients in the 5-day group 








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